Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856934 | 0.83 | NPSR1 (0.46) | NPSR1HTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL30645252 | 0.83 | NPSR1 (0.46) | NPSR1HTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL27188911 | 0.82 | KDM4E (0.50) | NPSR1HTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL28479368 | 0.81 | NPSR1 (0.42) | NPSR1HTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL28395736 | 0.72 | KDM4E (0.41) | NPSR1HTTL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL6251478 | 0.72 | LMNA (0.47) | NPSR1HTTL3MBTL1LMNAMAPT | |
| SCHEMBL856751 | 0.71 | MME (0.40) | NPSR1ALDH1A1 | |
| SCHEMBL30645250 | 0.71 | MME (0.40) | NPSR1ALDH1A1 | |
| SCHEMBL29448052 | 0.71 | NPSR1 (0.64) | NPSR1HTTL3MBTL1LMNAKDM4E | |
| SCHEMBL9172913 | 0.71 | NPSR1 (0.64) | NPSR1HTTL3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925330-A | Preparation method of altimezole | 上海阿达玛斯试剂有限公司 | 2020-11-13 | — | — | CN | claimed |
| CN-112225700-B | Preparation method of atemezole | 湖南新合新生物医药有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-112225700-A | Preparation method of altimezole | 湖南新合新生物医药有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-111925330-A | Preparation method of altimezole | 上海阿达玛斯试剂有限公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-111925330-A | Preparation method of altimezole | 上海阿达玛斯试剂有限公司 | 2020-11-13 | — | — | CN | disclosed |