SCHEMBL28489840

SCHEMBL28489840

C=C(C)C(=O)OC(C)C(N)(CC)S(=O)(=O)O.[NaH]

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28340199 0.98 TSHR (0.36) TSHRTHRB
SCHEMBL28820021 0.82 TSHR (0.32) TSHRTHRB
SCHEMBL4772046 0.78 TSHR (0.34) TSHR
SCHEMBL5203855 0.77 TSHR (0.41) TSHRTHRB
SCHEMBL28428711 0.77 TSHR (0.36) TSHRTHRB
Hydrochloric Acid SCHEMBL3826580 0.76 TSHR (0.40) TSHRTHRB
SCHEMBL28991919 0.75 TSHR (0.33) TSHR
SCHEMBL1535929 0.74 TSHR (0.37) TSHR
SCHEMBL2192060 0.73 TSHR (0.44) TSHRTHRB
SCHEMBL7601293 0.72 TSHR (0.36) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107141409-B Preparation method of paper reinforcing agent 广东省造纸研究所 2021-05-18 CN disclosed
CN-108102028-B Water-in-water amphoteric polyacrylamide emulsion and preparation method thereof 山东诺尔生物科技有限公司 2020-11-13 CN disclosed