Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 20/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 20/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 19/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045001 | 0.87 | ADORA2A (0.68) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL2980888 | 0.84 | ADORA2A (0.71) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL4047854 | 0.84 | ADORA2A (0.74) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL4047697 | 0.83 | ADORA2A (0.73) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL13322071 | 0.82 | ADORA2A (0.86) | ADORA2AADORA2BADORA1ADORA3 | |
| Vipadenant SCHEMBL29359313 | 0.82 | ADORA2A (1.00) | ADORA2AADORA2BADORA1ADORA3 | |
| Vipadenant SCHEMBL29421124 | 0.82 | ADORA2A (1.00) | ADORA2AADORA2BADORA1ADORA3 | |
| Vipadenant SCHEMBL2849027 | 0.82 | ADORA2A (1.00) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL4048578 | 0.80 | ADORA2A (0.65) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL4046292 | 0.80 | ADORA2A (0.85) | ADORA2AADORA2BADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117308-A1 | POLYMORPHS AND SOLVATES OF A PHARMACEUTICAL AND METHODS OF MAKING | Biogen Idec MA Inc. (US) | 2009-11-18 | — | — | EP | claimed |
| WO-2008086201-A1 | POLYMORPHS AND SOLVATES OF A PHARMACEUTICAL AND METHODS OF MAKING | BIOGEN IDEC MA INC. (US) | 2008-07-17 | — | — | WO | claimed |
| US-20100130515-A1 | Polymorphs and solvates of a pharmaceutical and method of making | BIOGEN IDEC INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100130515-A1 | Polymorphs and solvates of a pharmaceutical and method of making | BIOGEN IDEC INC. (US) | 2010-05-27 | — | — | US | disclosed |
| US-20100130515-A1 | Polymorphs and solvates of a pharmaceutical and method of making | BIOGEN IDEC INC. (US) | 2010-05-27 | — | — | US | disclosed |
| EP-2117308-A1 | POLYMORPHS AND SOLVATES OF A PHARMACEUTICAL AND METHODS OF MAKING | Biogen Idec MA Inc. (US) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008086201-A1 | POLYMORPHS AND SOLVATES OF A PHARMACEUTICAL AND METHODS OF MAKING | BIOGEN IDEC MA INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008086201-A1 | POLYMORPHS AND SOLVATES OF A PHARMACEUTICAL AND METHODS OF MAKING | BIOGEN IDEC MA INC. (US) | 2008-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130515-A1 | Polymorphs and solvates of a pharmaceutical and method of making | CYP3A7, CYP2D6, CYP3A5 | ADORA2A 832/4885ADORA2B 399/4885ADORA1 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.