Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.63 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.63 |
| ▸ | NOS3 | P29474 | 4/20 | 0.60 |
| ▸ | NOS1 | P29475 | 4/20 | 0.60 |
| ▸ | NOS2 | P35228 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490266 | 1.00 | SMN1; SMN2 (0.64) | SMN1; SMN2HDAC3ADAM17HDAC1HDAC2 | |
| SCHEMBL28481411 | 0.86 | NOS3 (0.72) | SMN1; SMN2HDAC3ADAM17HDAC1HDAC2 | |
| SCHEMBL28481413 | 0.86 | NOS3 (0.72) | SMN1; SMN2HDAC3ADAM17HDAC1HDAC2 | |
| SCHEMBL28483945 | 0.84 | KMT2A (0.70) | SMN1; SMN2NOS3NOS1NOS2TRPA1 | |
| SCHEMBL28483947 | 0.84 | KMT2A (0.70) | SMN1; SMN2NOS3NOS1NOS2TRPA1 | |
| SCHEMBL28483777 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2CYP1A2TRPM8UTS2RMEN1 | |
| SCHEMBL1559044 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL31440320 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL28483776 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2CYP1A2TRPM8UTS2RMEN1 | |
| SCHEMBL1557401 | 0.82 | SMN1; SMN2 (0.71) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111807983-A | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2020-10-23 | — | — | CN | claimed |
| CN-111807983-B | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2022-11-01 | — | — | CN | disclosed |
| CN-111807983-A | Cinnamic acid derivative and preparation method thereof | 五邑大学 | 2020-10-23 | — | — | CN | disclosed |