Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28492017 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TP53HTTHSD17B10MAPT | |
| SCHEMBL28490326 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TP53HTTHSD17B10MAPT | |
| SCHEMBL6543446 | 0.81 | CMA1 (0.44) | ALDH1A1LMNACMA1AKR1C3TSHR | |
| SCHEMBL4910313 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAAKR1C3 | |
| SCHEMBL4910307 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAAKR1C3 | |
| SCHEMBL8915258 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TP53HTTHSD17B10MAPT | |
| SCHEMBL8915262 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TP53HTTHSD17B10MAPT | |
| SCHEMBL8915252 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TP53HTTHSD17B10MAPT | |
| SCHEMBL2665474 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TP53HTTHSD17B10MAPT | |
| SCHEMBL9483908 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TP53HTTHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808057-B | Suzuki reaction using alpha-O-alkenyl sulfone as electrophile and application thereof | 四川大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-111808089-B | Preparation method of drug eprogliflozin for treating diabetes or derivative thereof | 四川大学华西医院 | 2023-04-11 | — | — | CN | disclosed |
| CN-111808089-A | Preparation method of drug eprogliflozin for treating diabetes or derivative thereof | 四川大学华西医院 | 2020-10-23 | — | — | CN | disclosed |
| CN-111808057-A | Suzuki reaction using alpha-O-alkenylsulfone as electrophile and use thereof | 四川大学 | 2020-10-23 | — | — | CN | disclosed |