Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TEC | P42680 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 4/20 | 0.33 |
| ▸ | JAK1 | P23458 | 4/20 | 0.33 |
| ▸ | JAK3 | P52333 | 4/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18285530 | 1.00 | BTK (0.35) | BTKEGFRTECCD69JAK2 | |
| SCHEMBL18285529 | 1.00 | BTK (0.35) | BTKEGFRTECCD69JAK2 | |
| SCHEMBL18285525 | 1.00 | BTK (0.35) | BTKEGFRTECCD69JAK2 | |
| SCHEMBL18818279 | 0.88 | HCAR1 (0.41) | BTKJAK2JAK1 | |
| SCHEMBL18818280 | 0.88 | HCAR1 (0.41) | BTKJAK2JAK1 | |
| SCHEMBL30111817 | 0.88 | HCAR1 (0.41) | BTKJAK2JAK1 | |
| SCHEMBL18285718 | 0.88 | HCAR1 (0.41) | BTKJAK2JAK1 | |
| SCHEMBL18289981 | 0.88 | HCAR1 (0.41) | BTKJAK2JAK1 | |
| SCHEMBL25466268 | 0.86 | JAK2 (0.33) | BTKJAK2JAK1JAK3 | |
| SCHEMBL18285554 | 0.80 | BTK (0.45) | BTKEGFRTECCD69JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113149983-B | Tyrosine kinase inhibitors | 普林斯匹亚生物制药公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-113149983-A | Tyrosine kinase inhibitors | 普林斯匹亚生物制药公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-106459049-B | Tyrosine kinase inhibitors | 普林斯匹亚生物制药公司 | 2020-11-27 | — | — | CN | disclosed |