SCHEMBL28490665

SCHEMBL28490665

CNCC(Nc1ncnc2c(C(=O)O)ccnc12)c1ccc(F)c(Br)c1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 20/20 0.84
RPS6KB1 P23443 7/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28490662 1.00 AKT1 (0.84) AKT1RPS6KB1
SCHEMBL20178093 0.91 AKT1 (1.00) AKT1RPS6KB1
SCHEMBL15762671 0.91 AKT1 (1.00) AKT1RPS6KB1
SCHEMBL28487123 0.89 AKT1 (0.84) AKT1RPS6KB1
SCHEMBL28487122 0.89 AKT1 (0.84) AKT1RPS6KB1
SCHEMBL28488181 0.86 AKT1 (0.63) AKT1RPS6KB1
Ammonia Solution, Strong SCHEMBL17076977 0.83 AKT1 (0.63) AKT1RPS6KB1
SCHEMBL15762415 0.83 AKT1 (1.00) AKT1RPS6KB1
SCHEMBL20178088 0.83 AKT1 (1.00) AKT1RPS6KB1
SCHEMBL28480348 0.83 AKT1 (0.71) AKT1RPS6KB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793254-B Azaquinazoline carboxamide derivatives 默克专利有限公司 2020-10-23 CN disclosed