Butylated Hydroxytoluene

Butylated Hydroxytoluene

SCHEMBL28491963

CC(C)C[AlH2].Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1.Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.69
ALDH1A1 P00352 4/20 0.69
CA2 P00918 4/20 0.69
POLB P06746 1/20 0.69
TYR P14679 1/20 0.69
HSPA5 P11021 1/20 0.56
HIF1A Q16665 5/20 0.55
CYP2C9 P11712 5/20 0.55
CYP2C19 P33261 5/20 0.55
CYP2D6 P10635 3/20 0.49
HSD17B10 Q99714 1/20 0.49
CA1 P00915 2/20 0.48
CYP1A2 P05177 4/20 0.46
TSHR P16473 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPSR1 Q6W5P4 3/20 0.46
CYP3A4 P08684 2/20 0.46
MAPK1 P28482 2/20 0.46
BLM P54132 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylated Hydroxytoluene SCHEMBL127920 0.85 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL28906266 0.84 SMN1; SMN2 (0.82) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL28891136 0.83 SMN1; SMN2 (0.90) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL19585114 0.83 SMN1; SMN2 (0.90) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL453824 0.83 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL3950 0.83 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL7955850 0.81 SMN1; SMN2 (0.64) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL10753112 0.81 SMN1; SMN2 (0.64) SMN1; SMN2ALDH1A1CA2POLBTYR
SCHEMBL225677 0.81 SMN1; SMN2 (0.86) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL11859223 0.81 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250341-B Catalyst system containing metallocene compound and method for catalyzing olefin polymerization by using catalyst system 北京引发科技有限公司 2020-12-11 CN disclosed