Butylated Hydroxytoluene

Butylated Hydroxytoluene

SCHEMBL3950

Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 1.00
ALDH1A1 P00352 5/20 1.00
CA2 P00918 4/20 1.00
POLB P06746 1/20 1.00
TYR P14679 1/20 1.00
HSPA5 P11021 1/20 0.68
CA1 P00915 2/20 0.67
CYP2C9 P11712 4/20 0.65
CYP2C19 P33261 4/20 0.65
HIF1A Q16665 3/20 0.65
CYP2D6 P10635 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CYP1A2 P05177 3/20 0.56
ALOX15 P16050 3/20 0.56
MAPT P10636 2/20 0.56
HPN P05981 1/20 0.56
SIRT5 Q9NXA8 1/20 0.56
PTGS1 P23219 1/20 0.55
PTGS2 P35354 1/20 0.55
GAA P10253 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylated Hydroxytoluene SCHEMBL453824 1.00 SMN1; SMN2 (1.00) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL864242 0.97 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL20660368 0.97 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL11857289 0.97 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL11859223 0.97 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL7075597 0.97 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL4170581 0.97 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL9343307 0.97 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL9343306 0.97 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR
Butylated Hydroxytoluene SCHEMBL31314972 0.97 SMN1; SMN2 (0.95) SMN1; SMN2ALDH1A1CA2POLBTYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 295547 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144759-A1 Surface-modified plant-derived extracellular vesicles and targeted drug delivery system using the same KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-05-28 US claimed
EP-4424802-B1 LUBRICANT COMPOSITION NOF CORP (JP) 2026-05-27 EP claimed
EP-4747328-A1 COMPOSITIONS COMPRISING DIFLUOROPROPENE AND USES THEREOF The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4748882-A1 NON-HALOGENATED HIGHLY FLAME RETARDANT COMPOSITE THERMOPLASTIC RESIN COMPOSITIONS CONTAINING RECYCLED RESINS AND MOLDED ARTICLES MADE THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2026-05-27 EP claimed
EP-4747322-A1 METHODS AND SYSTEMS USING 1,1-DIFLUOROPROPENE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747327-A1 METHODS AND APPARATUS USING DIFLUOROPROPENE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4126057-B9 COMPOSITION HAVING IMPROVED VOLUNTARY ACCEPTANCE ELANCO ANIMAL HEALTH GMBH (DE) 2026-05-27 EP claimed
EP-4747325-A1 LOW GWP COMPOSITIONS COMPRISING HFO-1252ZC AND USES THEREOF The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747323-A1 BLEND COMPOSITIONS CONTAINING DIFLUOROPROPENE The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
EP-4747324-A1 METHODS AND EQUIPMENT FOR TRANSPORTING, TRANSFERRING, STORING AND USING REFRIGERANTS The Chemours Company FC, LLC (US) 2026-05-27 EP claimed
US-3954682-A GRANULES OR BEADS GAF CORPORATION (US) 1976-05-04 US claimed
US-3953387-A CONTAINING A CARBOXYLIC ACID AND A HINDERED PHENOL ATLANTIC RICHFIELD COMPANY (US) 1976-04-27 US claimed
US-3952072-A MOLDING MATERIALS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1976-04-20 US claimed
US-3950305-A PHOSPHOROUS ACID TRIESTER HOECHST AKTIENGESELLSCHAFT (DT) 1976-04-13 US claimed
US-3944695-A Heat printing sheet TOYO SODA MANUFACTURING CO., LTD. (JA) 1976-03-16 US claimed
US-3941747-A 2,6-DI-TERT-BUTYL-4-METHYL-PHENOL AND 2,6-DI-TERT-BUTYL-4-ETHYL-PHENOL GULF OIL CORPORATION (US) 1976-03-02 US claimed
US-3940451-A Process of recovering BHT values from mother liquors of the crystallization of BHT obtained by alkylating p-cresol with isobutylene COMPANIA QUIMICA AMEYAL, A CORP. OF MEXICO (MX) 1976-02-24 US claimed
US-3933720-A Polychloroprene type adhesive compositions NIPPON OIL COMPANY LTD. (JA) 1976-01-20 US claimed
US-3933719-A Polychloroprene-base adhesive composition NIPPON OIL COMPANY LTD. (JA) 1976-01-20 US claimed
US-3933924-A Process for preparing hydroxydiphenyl BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US claimed