Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 8/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495609 | 1.00 | AOC3 (0.44) | AOC3FNTAFNTBOPRD1GRM5 | |
| SCHEMBL28497819 | 0.87 | AOC3 (0.47) | AOC3FNTAFNTBDDB1CRBN | |
| SCHEMBL28501731 | 0.87 | AOC3 (0.47) | AOC3FNTAFNTBDDB1CRBN | |
| SCHEMBL22713860 | 0.86 | MAOA (0.43) | AOC3FNTAFNTBOPRD1DDB1 | |
| SCHEMBL28497758 | 0.86 | MAOA (0.43) | AOC3FNTAFNTBOPRD1DDB1 | |
| SCHEMBL28499188 | 0.86 | AOC3 (0.41) | AOC3FNTAFNTBDDB1CRBN | |
| SCHEMBL28513384 | 0.86 | AOC3 (0.49) | AOC3FNTAFNTBDDB1CRBN | |
| SCHEMBL22713826 | 0.86 | AOC3 (0.49) | AOC3FNTAFNTBDDB1CRBN | |
| SCHEMBL22713739 | 0.86 | AOC3 (0.41) | AOC3FNTAFNTBDDB1CRBN | |
| SCHEMBL28502584 | 0.85 | AOC3 (0.49) | AOC3FNTAFNTBDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988109-B | Amine compound for inhibiting SSAO/VAP-1 and application thereof | 广东东阳光药业有限公司 | 2020-12-29 | — | — | CN | disclosed |