Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | TOP1 | P11387 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495101 | 0.81 | HTT (0.48) | MEN1KMT2AL3MBTL1HTTLOXL2 | |
| SCHEMBL28498767 | 0.80 | SCN9A (0.39) | MEN1KMT2AL3MBTL1TOP1HPGD | |
| SCHEMBL28492187 | 0.72 | TOP1 (0.40) | MEN1KMT2AL3MBTL1HTTLOXL2 | |
| SCHEMBL28494857 | 0.70 | ADORA2A (0.43) | MEN1KMT2AL3MBTL1HTTLOXL2 | |
| SCHEMBL18153300 | 0.69 | MEN1 (0.51) | MEN1KMT2AL3MBTL1HTTALDH1A1 | |
| SCHEMBL24309569 | 0.68 | TDP1 (0.70) | MEN1KMT2AL3MBTL1HTTLOXL2 | |
| SCHEMBL3410924 | 0.66 | ALDH1A1 (0.61) | MEN1KMT2AL3MBTL1HTTMAPK1 | |
| SCHEMBL17609003 | 0.64 | ATM (0.59) | MEN1KMT2AL3MBTL1HTTLOXL2 | |
| SCHEMBL18153341 | 0.63 | ALDH1A1 (0.41) | MEN1KMT2AL3MBTL1HTTALDH1A1 | |
| SCHEMBL28252052 | 0.63 | MEN1 (0.80) | MEN1KMT2AL3MBTL1HTTTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079830-B | Inhibitor containing fused ring derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-112079830-A | Fused ring-containing derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2020-12-15 | — | — | CN | disclosed |