Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17841962 | 1.00 | CYP1A2 (0.60) | CYP1A2ALDH1A1HSD17B10THRBHPGD | |
| SCHEMBL3787526 | 0.89 | CYP1A2 (0.65) | CYP1A2ALDH1A1HSD17B10THRBHPGD | |
| SCHEMBL5615235 | 0.89 | CYP1A2 (0.52) | CYP1A2ALDH1A1HSD17B10THRBHPGD | |
| SCHEMBL3710185 | 0.85 | CYP2A6 (0.73) | CYP1A2ALDH1A1HSD17B10THRBHPGD | |
| SCHEMBL476875 | 0.85 | CYP2A6 (0.73) | CYP1A2ALDH1A1HSD17B10THRBHPGD | |
| Benzo[E]Pyrene SCHEMBL9998154 | 0.84 | HSD17B10 (0.84) | CYP1A2ALDH1A1HSD17B10THRBHPGD | |
| SCHEMBL2233815 | 0.84 | HSD17B10 (0.75) | CYP1A2ALDH1A1HSD17B10THRBHPGD | |
| Chrysene SCHEMBL18546560 | 0.84 | HSD17B10 (0.75) | CYP1A2ALDH1A1HSD17B10THRBHPGD | |
| SCHEMBL17841964 | 0.83 | HPRT1 (0.58) | CYP1A2ALDH1A1HSD17B10THRBHPGD | |
| SCHEMBL22211948 | 0.83 | CYP1A2 (0.64) | CYP1A2ALDH1A1HSD17B10THRBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142242-A2 | CATHETER HAVING INTERNAL MECHANISMS TO ENCOURAGE BALLOON RE-FOLDING | Boston Scientific Limited (BB) | 2010-01-13 | — | — | EP | disclosed |
| WO-2008124480-A2 | CATHETER HAVING INTERNAL MECHANISMS TO ENCOURAGE BALLOON RE-FOLDING | BOSTON SCIENTIFIC LIMITED (BB) | 2008-10-16 | — | — | WO | disclosed |
| EP-1329225-A2 | Transdermal device containing polyvinylpyrrolidone as solubility enhancer | NOVEN PHARMACEUTICALS, INC. (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0737066-B1 | TRANSDERMAL DEVICE CONTAINING POLYVINYLPYRROLIDONE AS SOLUBILITY ENHANCER | NOVEN PHARMA (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-0737066-A1 | TRANSDERMAL DEVICE CONTAINING POLYVINYLPYRROLIDONE AS SOLUBILITY ENHANCER | NOVEN PHARMACEUTICALS, INC. (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018603-A1 | TRANSDERMAL DEVICE CONTAINING POLYVINYLPYRROLIDONE AS SOLUBILITY ENHANCER | NOVEN PHARMACEUTICALS, INC. (US) | 1995-07-13 | — | — | WO | disclosed |