Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 3/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2843551 | 0.92 | PTGER4 (0.46) | PTGER4CASP3KLK7KLK5CA1 | |
| SCHEMBL2842850 | 0.90 | KLK7 (0.44) | PTGER4CASP3KLK7KLK5CA1 | |
| SCHEMBL3625983 | 0.89 | KLK7 (0.45) | PTGER4CASP3KLK7KLK5CA1 | |
| SCHEMBL2845471 | 0.89 | KDM1A (0.44) | PTGER4CASP3KLK7KLK5CA1 | |
| SCHEMBL2849323 | 0.84 | CA1 (0.43) | PTGER4CASP3KLK7KLK5CA1 | |
| SCHEMBL2842792 | 0.83 | HDAC1 (0.49) | PTGER4CASP3KLK7KLK5 | |
| SCHEMBL2845514 | 0.83 | CTSS (0.48) | PTGER4CASP3KLK7KLK5 | |
| SCHEMBL2845533 | 0.83 | CTSS (0.48) | PTGER4CASP3KLK7KLK5 | |
| SCHEMBL2845513 | 0.83 | KLK7 (0.46) | PTGER4CASP3KLK7KLK5CA1 | |
| SCHEMBL2848265 | 0.82 | KLK5 (0.64) | CASP3KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216803-A1 | ORNITHINE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-2141147-A1 | ORNITHINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216803-A1 | ORNITHINE DERIVATIVE | PTGER4, OXER1, ODC1 | PTGER4 1/4885CASP3 3838/4885KLK7 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.