Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28493530

C1CCOC1.c1ccc(COC[C@H]2CO2)cc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.49
TDP1 Q9NUW8 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
TSHR P16473 2/20 0.44
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MGLL Q99685 2/20 0.41
HRH4 Q9H3N8 4/20 0.41
HRH3 Q9Y5N1 4/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153049 0.90 LMNA (0.57) LMNATDP1TAAR1TSHRMEN1
SCHEMBL306297 0.90 LMNA (0.57) LMNATDP1TAAR1TSHRMEN1
SCHEMBL715660 0.90 LMNA (0.57) LMNATDP1TAAR1TSHRMEN1
SCHEMBL16993434 0.88 LMNA (0.55) LMNATDP1TAAR1TSHRMEN1
Water SCHEMBL8913477 0.88 LMNA (0.55) LMNATDP1TAAR1TSHRMEN1
Ammonia Solution, Strong SCHEMBL28849284 0.88 LMNA (0.55) LMNATDP1TAAR1TSHRMEN1
Ethylene SCHEMBL27465209 0.86 LMNA (0.54) LMNATDP1TAAR1TSHRMEN1
SCHEMBL23658091 0.86 LMNA (0.48) LMNATDP1TAAR1TSHRMEN1
SCHEMBL10895327 0.86 LMNA (0.48) LMNATDP1TAAR1TSHRMEN1
SCHEMBL7594738 0.86 LMNA (0.48) LMNATDP1TAAR1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112110951-B Carex C-ring framework compound, and synthesis method and application thereof 四川大学 2021-05-18 CN disclosed
CN-112110951-A Carex C-ring framework compound, and synthesis method and application thereof 四川大学 2020-12-22 CN disclosed