Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | CDK4 | P11802 | 5/20 | 0.47 |
| ▸ | CCND1 | P24385 | 5/20 | 0.47 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 11/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22189181 | 0.86 | PARP14 (0.51) | KIF11CDC25BPARP14 | |
| SCHEMBL30022189 | 0.86 | PARP14 (0.51) | KIF11CDC25BPARP14 | |
| SCHEMBL25302324 | 0.85 | KIF11 (0.57) | KIF11CDK4CCND1PARP14GABRP | |
| SCHEMBL29177751 | 0.80 | KIF11 (0.46) | KIF11CDC25BPARP14BCHE | |
| SCHEMBL29177985 | 0.80 | KIF11 (0.46) | KIF11CDK4CCND1CDC25BPARP14 | |
| Biphenyl SCHEMBL29177843 | 0.79 | PARP14 (0.47) | KIF11CDC25BPARP14GABRPGABRD | |
| SCHEMBL30302765 | 0.79 | PARP14 (0.47) | KIF11CDC25BPARP14GABRPGABRD | |
| SCHEMBL29170881 | 0.79 | KIF11 (0.47) | KIF11CDK4CCND1PARP14GABRP | |
| SCHEMBL29199250 | 0.78 | KIF11 (0.49) | KIF11CDK4CCND1PARP14GABRP | |
| SCHEMBL28795757 | 0.77 | PARP14 (0.49) | CDK4CCND1PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428639-B | Double-spiro compound and organic light-emitting element comprising same | 株式会社LG化学 | 2020-10-30 | — | — | CN | claimed |
| CN-108137525-B | Heterocyclic compound and organic light emitting diode including the same | 株式会社LG化学 | 2021-12-28 | — | — | CN | disclosed |
| CN-107428639-B | Double-spiro compound and organic light-emitting element comprising same | 株式会社LG化学 | 2020-10-30 | — | — | CN | disclosed |