Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KYNU | Q16719 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.44 |
| ▸ | CPN1 | P15169 | 2/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848191 | 0.83 | ESR1 (0.43) | KYNUHIF1ALMNAKDM4EOPRK1 | |
| SCHEMBL679845 | 0.83 | CYP2C19 (0.52) | LMNA | |
| SCHEMBL681512 | 0.83 | CYP2C19 (0.52) | LMNA | |
| SCHEMBL681077 | 0.83 | CYP2C19 (0.52) | LMNA | |
| SCHEMBL1820061 | 0.81 | KYNU (0.51) | KYNUHIF1ALMNAKDM4ECPN1 | |
| SCHEMBL29687004 | 0.81 | KYNU (0.51) | KYNUHIF1ALMNAKDM4ECPN1 | |
| SCHEMBL2847001 | 0.80 | AKR1C3 (0.50) | LMNA | |
| SCHEMBL4957164 | 0.80 | KYNU (0.53) | KYNUHIF1ALMNAKDM4ECPN1 | |
| SCHEMBL6366844 | 0.80 | KYNU (0.53) | KYNUHIF1ALMNAKDM4ECPN1 | |
| SCHEMBL31188945 | 0.80 | KYNU (0.53) | KYNUHIF1ALMNAKDM4ECPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |