Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 3/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465844 | 0.83 | MAPT (0.49) | MAP4K4ALDH1A1MAPTLMNAPRKCQ | |
| SCHEMBL12465843 | 0.83 | MAPT (0.49) | MAP4K4ALDH1A1MAPTLMNAPRKCQ | |
| SCHEMBL30772278 | 0.83 | MAPT (0.49) | MAP4K4ALDH1A1MAPTLMNAPRKCQ | |
| SCHEMBL30514215 | 0.83 | USP30 (0.34) | ALDH1A1MAPTLMNAUSP30UCHL1 | |
| SCHEMBL28488389 | 0.80 | ALDH1A1 (0.37) | MAP4K4ALDH1A1MAPTLMNA | |
| SCHEMBL27930668 | 0.76 | ALDH1A1 (0.37) | ALDH1A1MAPTLMNA | |
| SCHEMBL17461348 | 0.75 | MAPT (0.40) | ALDH1A1MAPT | |
| SCHEMBL2338338 | 0.72 | MAP4K4 (0.56) | MAP4K4NR1H2NR1H3ALDH1A1MAPT | |
| SCHEMBL2342450 | 0.72 | MAP4K4 (0.56) | MAP4K4NR1H2NR1H3ALDH1A1MAPT | |
| SCHEMBL2338334 | 0.72 | MAP4K4 (0.56) | MAP4K4NR1H2NR1H3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116942672-A | Crystalline salts of B-RAF kinase inhibitors | 徐诺药业公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-111818924-B | Crystalline salts of B-RAF kinase inhibitors | 徐诺药业公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111818924-A | Crystalline salts of B-RAF kinase inhibitors | 徐诺药业公司 | 2020-10-23 | — | — | CN | disclosed |