Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13872055 | 0.90 | KMT2A (0.68) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL8252454 | 0.86 | KMT2A (0.72) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL5536842 | 0.86 | KMT2A (0.69) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL20631562 | 0.86 | HPGD (0.86) | MEN1KMT2AHPGDALDH1A1KDM4E | |
| SCHEMBL23085963 | 0.85 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL3902704 | 0.85 | KMT2A (0.67) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL5537347 | 0.85 | KMT2A (0.70) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL3900270 | 0.85 | KMT2A (0.70) | MEN1KMT2AHPGDALDH1A1HTT | |
| SCHEMBL29188760 | 0.85 | KMT2A (0.70) | MEN1KMT2AHPGDALDH1A1GPR119 | |
| SCHEMBL22127506 | 0.85 | MAPT (0.61) | MEN1KMT2AHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820287-A | Magnolol derivative, and preparation method and application thereof | 中国药科大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-107226808-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |
| CN-107226807-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |