⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1232757 | 1.00 | — | — | |
| SCHEMBL7296321 | 1.00 | — | — | |
| Methylamine SCHEMBL28554106 | 0.96 | NPC1 (0.44) | — | |
| Dimethylamine SCHEMBL27876905 | 0.94 | NPC1 (0.43) | — | |
| SCHEMBL27928465 | 0.94 | NPC1 (0.43) | — | |
| Dimethylamine SCHEMBL27907968 | 0.92 | KMT2A (0.42) | — | |
| SCHEMBL12235253 | 0.83 | NPC1 (0.51) | — | |
| SCHEMBL14386089 | 0.83 | NPC1 (0.51) | — | |
| SCHEMBL5834937 | 0.83 | NPC1 (0.51) | — | |
| SCHEMBL4440609 | 0.82 | NPC1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107488163-A | The preparation method of (2 thienyl) 1 propyl alcohol of one kind (S) 3 N, N disubstituted amidos 1 | 天台宜生生化科技有限公司 | 2017-12-19 | — | — | CN | claimed |
| CN-103014088-A | Biological preparation method of (S)-3-methylamino-(2-thienyl)-1-propyl alcohol | ENZYMEWORKS INC | 2013-04-03 | — | — | CN | claimed |
| CN-101012219-A | Method of preparing dulouxetine | UNIV TIANJIN (CN) | 2007-08-08 | — | — | CN | claimed |
| US-12365927-B2 | Engineered ketoreductase polypeptides | CODEXIS, INC. (US) | 2025-07-22 | — | — | US | disclosed |
| US-20250075147-A1 | FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS | OSMO LABS, PBC | 2025-03-06 | — | — | US | disclosed |
| CN-114214295-B | Carbonyl reductase and method for synthesizing (S) -3- (dimethylamino) -1- (2-thienyl) -1-propanol | 江苏海洋大学 | 2024-05-03 | — | — | CN | disclosed |
| US-20230104779-A1 | ENGINEERED KETOREDUCTASE POLYPEPTIDES | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2023-04-06 | — | — | US | disclosed |
| US-11512332-B2 | Engineered ketoreductase polypeptides | CODEXIS, INC. (US) | 2022-11-29 | — | — | US | disclosed |
| CN-114560892-A | Chiral tridentate nitrogen phosphine ligand synthesized based on ferrocene skeleton and application thereof | 广东工业大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-114214295-A | Carbonyl reductase and method for synthesizing (S) -3- (dimethylamino) -1- (2-thienyl) -1-propanol | 江苏海洋大学 | 2022-03-22 | — | — | CN | disclosed |
| CN-113249349-B | Mutant alcohol dehydrogenase, recombinant vector, preparation method and application thereof | 中国科学院苏州生物医学工程技术研究所 | 2022-01-25 | — | — | CN | disclosed |
| EP-0475214-B1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LTD (JP) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994018188-A1 | 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL[B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS | THE UPJOHN COMPANY (US) | 1994-08-18 | — | — | WO | disclosed |
| US-5326785-A | Arteriosclerosis andn diseases of the circulatory system | SUNTORY LIMITED (JP) | 1994-07-05 | — | — | US | disclosed |
| US-5232941-A | Therapeutic agents for diseases of the circulatory system | SUNTORY LIMITED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0475214-A1 | Caffeic acid derivatives and pharmaceutical compositions containing the same | SUNTORY LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4954506-A | ANALGESICS, NARCOTIC ANTAGONISTS | BOC, INC. (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| US-4916142-A | N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and their use as analgesics | BOC, INC. (US) | 1990-04-10 | — | — | US | disclosed |
| US-4912109-A | Narcotic antagonist | BOC, INC. (US) | 1990-03-27 | — | — | US | disclosed |