Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525329 | 0.89 | NPC1 (0.53) | NPC1RAB9AKMT2AHTR1ACES2 | |
| SCHEMBL3229012 | 0.89 | NPC1 (0.53) | NPC1RAB9AKMT2AHTR1ACES2 | |
| SCHEMBL5834937 | 0.87 | NPC1 (0.51) | NPC1RAB9AKMT2AHTR1ACES2 | |
| SCHEMBL2964417 | 0.87 | NPC1 (0.51) | NPC1RAB9AKMT2AHTR1ACES2 | |
| SCHEMBL1264082 | 0.87 | NPC1 (0.55) | NPC1RAB9AKMT2AHTR1ACES2 | |
| SCHEMBL14386089 | 0.87 | NPC1 (0.51) | NPC1RAB9AKMT2AHTR1ACES2 | |
| SCHEMBL5684870 | 0.87 | NPC1 (0.51) | NPC1RAB9AKMT2AHTR1ACES2 | |
| SCHEMBL1232311 | 0.87 | NPC1 (0.55) | NPC1RAB9AKMT2AHTR1ACES2 | |
| SCHEMBL1200723 | 0.87 | NPC1 (0.55) | NPC1RAB9AKMT2AHTR1ACES2 | |
| SCHEMBL2174566 | 0.87 | NPC1 (0.51) | NPC1RAB9AKMT2AHTR1ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090123514-A1 | Electropolymerizable Monomers and Polymeric Coatings on Implantable Devices Prepared Therefrom | ELUTEX LTD. (IL) | 2009-05-14 | — | — | US | claimed |
| JP-2009501828-A | — | — | 2009-01-22 | — | — | JP | claimed |
| EP-1904119-A2 | ELECTROPOLYMERIZABLE MONOMERS AND POLYMERIC COATINGS ON IMPLANTABLE DEVICES PREPARED THEREFROM | Elutex Ltd. (IL) | 2008-04-02 | — | — | EP | claimed |
| WO-2007010536-A2 | ELECTROPOLYMERIZABLE MONOMERS AND POLYMERIC COATINGS ON IMPLANTABLE DEVICES PREPARED THEREFROM | ELUTEX LTD. (IL) | 2007-01-25 | — | — | WO | claimed |
| US-20090232867-A1 | Modified conductive surfaces having active substances attached thereto | ELUTEX LTD. (IL) | 2009-09-17 | — | — | US | disclosed |
| US-20090123514-A1 | Electropolymerizable Monomers and Polymeric Coatings on Implantable Devices Prepared Therefrom | ELUTEX LTD. (IL) | 2009-05-14 | — | — | US | disclosed |
| EP-1904119-A2 | ELECTROPOLYMERIZABLE MONOMERS AND POLYMERIC COATINGS ON IMPLANTABLE DEVICES PREPARED THEREFROM | Elutex Ltd. (IL) | 2008-04-02 | — | — | EP | disclosed |
| EP-1768717-A2 | MODIFIED CONDUCTIVE SURFACES HAVING ACTIVE SUBSTANCES ATTACHED THERETO | Elutex Ltd. (IL) | 2007-04-04 | — | — | EP | disclosed |
| WO-2007010536-A2 | ELECTROPOLYMERIZABLE MONOMERS AND POLYMERIC COATINGS ON IMPLANTABLE DEVICES PREPARED THEREFROM | ELUTEX LTD. (IL) | 2007-01-25 | — | — | WO | disclosed |
| WO-2006008739-A2 | MODIFIED CONDUCTIVE SURFACES HAVING ACTIVE SUBSTANCES ATTACHED THERETO | ELUTEX LTD. (IL) | 2006-01-26 | — | — | WO | disclosed |
| US-20060013850-A1 | Electropolymerizable monomers and polymeric coatings on implantable devices prepared therefrom | ELUTEX LTD. (IL) | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090123514-A1 | Electropolymerizable Monomers and Polymeric Coatings on Implantable Devices Prepared Therefrom | ITK, ICAM1, ITGAM | NPC1 4837/4885RAB9A 4358/4885KMT2A 2872/4885 |
| US-20060013850-A1 | Electropolymerizable monomers and polymeric coatings on implantable devices prepared therefrom | ITK, ICAM1, ITGAM | NPC1 4837/4885RAB9A 4358/4885KMT2A 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.