Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175845 | 0.85 | PDPK1 (0.70) | PDPK1LOXL2CYP2A6PTGDR2RAB9A | |
| SCHEMBL5692672 | 0.83 | PDPK1 (0.64) | PDPK1LOXL2CYP2A6PTGDR2RAB9A | |
| SCHEMBL8407091 | 0.83 | PDPK1 (0.52) | PDPK1LOXL2CYP2A6PTGDR2FBP1 | |
| SCHEMBL28487238 | 0.83 | PDPK1 (0.52) | PDPK1LOXL2CYP2A6PTGDR2FBP1 | |
| SCHEMBL9089977 | 0.83 | PDPK1 (0.52) | PDPK1LOXL2CYP2A6PTGDR2FBP1 | |
| SCHEMBL16990890 | 0.82 | PDPK1 (0.56) | PDPK1ABL1BCRLOXL2CYP2A6 | |
| SCHEMBL9086913 | 0.82 | PDPK1 (0.51) | PDPK1ABL1BCRLOXL2CYP2A6 | |
| SCHEMBL636877 | 0.81 | PDPK1 (0.63) | PDPK1ABL1BCRLOXL2CYP2A6 | |
| SCHEMBL1951149 | 0.81 | PDPK1 (0.61) | PDPK1LOXL2CYP2A6PTGDR2RAB9A | |
| SCHEMBL28487118 | 0.80 | ABL1 (0.42) | PDPK1ABL1BCRLOXL2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909110-A | Preparation method of 2, 4-disubstituted thiazole compound | 浙江工业大学 | 2020-11-10 | — | — | CN | disclosed |