Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28509075 | 0.78 | HDAC6 (1.00) | HDAC6HDAC1MAPTMEN1KMT2A | |
| SCHEMBL28502625 | 0.75 | HDAC1 (0.63) | HDAC6HDAC1MAPTHDAC3HDAC4 | |
| SCHEMBL28502726 | 0.75 | HDAC1 (0.70) | HDAC6HDAC1MAPTMEN1KMT2A | |
| SCHEMBL28495217 | 0.75 | HDAC6 (0.70) | HDAC6HDAC1MAPTMEN1KMT2A | |
| SCHEMBL28504784 | 0.74 | HDAC1 (0.69) | HDAC6HDAC1MAPTMEN1KMT2A | |
| SCHEMBL28495211 | 0.72 | HDAC1 (0.78) | HDAC6HDAC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7105196 | 0.71 | NPC1 (0.70) | MAPTRXFP1CEPT1TSHRMEN1 | |
| SCHEMBL28504884 | 0.70 | HDAC6 (0.75) | HDAC6HDAC1MAPTMEN1KMT2A | |
| SCHEMBL29558498 | 0.68 | HDAC6 (0.71) | HDAC6HDAC1MAPTMEN1KMT2A | |
| SCHEMBL2639284 | 0.68 | HDAC1 (0.74) | HDAC6HDAC1MAPTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943892-B | Histone deacetylase subtype inhibitor thioacetylarylamine compound and application thereof | 上海中泽医药科技有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-111943892-A | Histone deacetylase subtype inhibitor thioacetylarylamine compound and application thereof | 上海中泽医药科技有限公司 | 2020-11-17 | — | — | CN | disclosed |