Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.64 |
| ▸ | PPARG | P37231 | 1/20 | 0.64 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.64 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.64 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.62 |
| ▸ | TNKS | O95271 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105775 | 0.87 | NPC1 (0.70) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7109169 | 0.86 | NPC1 (0.68) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL15702608 | 0.85 | SMN1; SMN2 (0.71) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL15702631 | 0.84 | NPC1 (0.73) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL2247579 | 0.82 | RAB9A (1.00) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL2243410 | 0.79 | KDM4E (0.76) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL4370566 | 0.78 | CHIA (0.77) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL24155564 | 0.77 | NPC1 (0.67) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL31170 | 0.76 | NPC1 (0.81) | NPC1RAB9AHSD17B10MEN1KMT2A | |
| SCHEMBL25318603 | 0.75 | UTRN (0.63) | NPC1RAB9AHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812319-B9 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RES VENTURES LTD (GB) | 2003-10-08 | — | — | EP | claimed |
| EP-0812319-B1 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RES VENTURES LTD (GB) | 2002-07-10 | — | — | EP | claimed |
| US-6034246-A | ANTICANCER AGENT | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-03-07 | — | — | US | claimed |
| EP-0812319-A1 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1997-12-17 | — | — | EP | claimed |
| WO-1996026932-A1 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-09-06 | — | — | WO | claimed |
| EP-0812319-B9 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RES VENTURES LTD (GB) | 2003-10-08 | — | — | EP | disclosed |
| EP-0812319-B1 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RES VENTURES LTD (GB) | 2002-07-10 | — | — | EP | disclosed |
| US-6034246-A | ANTICANCER AGENT | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-03-07 | — | — | US | disclosed |
| WO-1996026932-A1 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-09-06 | — | — | WO | disclosed |