Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30193840 | 0.87 | CMA1 (0.43) | CMA1GSK3AGSK3BSCN9AL3MBTL1 | |
| SCHEMBL25359325 | 0.87 | CMA1 (0.43) | CMA1GSK3AGSK3BSCN9AL3MBTL1 | |
| SCHEMBL26001081 | 0.84 | SCN9A (0.39) | CMA1GSK3AGSK3BSCN9AL3MBTL1 | |
| SCHEMBL28563929 | 0.83 | CHRM5 (0.44) | CMA1GSK3AGSK3BSCN9AL3MBTL1 | |
| SCHEMBL31478809 | 0.83 | CMA1 (0.39) | CMA1GSK3AGSK3BSCN9AL3MBTL1 | |
| SCHEMBL26001112 | 0.83 | CHRM5 (0.39) | CMA1GSK3AGSK3BSCN9AL3MBTL1 | |
| SCHEMBL25355571 | 0.82 | SCN9A (0.38) | CMA1GSK3AGSK3BSCN9AL3MBTL1 | |
| SCHEMBL25359029 | 0.81 | CMA1 (0.38) | CMA1GSK3AGSK3BSCN9AL3MBTL1 | |
| SCHEMBL25359718 | 0.80 | PTPN1 (0.37) | CMA1GSK3AGSK3BSCN9AL3MBTL1 | |
| SCHEMBL26001083 | 0.80 | KDM4E (0.37) | CMA1GSK3AGSK3BSCN9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108727367-B | Benzoxazinone compound containing pyridopyrimidinedione, preparation method and application thereof, and herbicide composition | 山东先达农化股份有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-110156767-B | Cycloalkane pyrimidine diketone compound, preparation method and application thereof, and pesticide herbicide | 南开大学 | 2020-12-11 | — | — | CN | disclosed |