Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25359718 | 0.93 | PTPN1 (0.37) | KDM4EHTTCMA1SCN9ACHRM5 | |
| SCHEMBL31478809 | 0.93 | CMA1 (0.39) | KDM4EHTTCMA1SCN9ACHRM5 | |
| SCHEMBL25359029 | 0.91 | CMA1 (0.38) | KDM4EHTTCMA1SCN9ACHRM5 | |
| SCHEMBL25358852 | 0.88 | SCN9A (0.37) | HTTSCN9AL3MBTL1CASP3 | |
| SCHEMBL30193711 | 0.88 | SCN9A (0.37) | HTTSCN9AL3MBTL1CASP3 | |
| SCHEMBL26001081 | 0.88 | SCN9A (0.39) | KDM4EHTTCMA1SCN9ACHRM5 | |
| SCHEMBL25355571 | 0.86 | SCN9A (0.38) | KDM4EHTTCMA1SCN9ACHRM5 | |
| SCHEMBL26001112 | 0.83 | CHRM5 (0.39) | KDM4EHTTCMA1SCN9ACHRM5 | |
| SCHEMBL25356340 | 0.82 | — | — | |
| SCHEMBL28495237 | 0.80 | CMA1 (0.43) | KDM4EHTTCMA1SCN9ACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4402133-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | Enko Chem, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-08-24 | — | — | US | disclosed |
| WO-2023044364-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827610-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, PPIF, CYP4X1 | KDM4E 1355/4885HTT 2250/4885CMA1 2038/4885 |
| US-20230265060-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PPIF, CYP4X1 | KDM4E 1360/4885HTT 2222/4885CMA1 2005/4885 |
| US-20230382876-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PPIF, CYP4X1 | KDM4E 1355/4885HTT 2250/4885CMA1 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.