Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765139 | 0.79 | PARP10 (0.68) | NPC1RAB9APARP15PARP10MAOB | |
| SCHEMBL16825194 | 0.71 | GRIN2B (0.57) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL31264796 | 0.70 | SMN1; SMN2 (0.65) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL20883219 | 0.70 | PARP10 (1.00) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL31264719 | 0.69 | SMN1; SMN2 (0.63) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL29873406 | 0.69 | PARP10 (0.72) | NPC1RAB9APARP15PARP10MAOB | |
| SCHEMBL4638452 | 0.69 | PARP10 (0.72) | NPC1RAB9APARP15PARP10MAOB | |
| SCHEMBL18297996 | 0.69 | SMN1; SMN2 (0.76) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL23850350 | 0.68 | SMN1; SMN2 (0.60) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL28659947 | 0.67 | SMN1; SMN2 (0.51) | NPC1CASP3RAB9ASENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112153968-A | Process for the preparation of alpha-carboxamide pyrrolidine derivatives | 生物基因公司 | 2020-12-29 | — | — | CN | disclosed |