Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.68 |
| ▸ | MAOB | P27338 | 3/20 | 0.68 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.68 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23541302 | 0.84 | MAOB (0.51) | PARP10MAOBPARP15PARP14 | |
| SCHEMBL2744895 | 0.84 | PARP10 (0.59) | PARP10MAOBPTGER1KCNH2LMNA | |
| SCHEMBL20883219 | 0.81 | PARP10 (1.00) | PARP10MAOBPARP15PARP14SCN3A | |
| SCHEMBL29873406 | 0.80 | PARP10 (0.72) | PARP10MAOBPARP15PARP14ALDH1A1 | |
| SCHEMBL30151716 | 0.80 | SYK (0.45) | PARP10MAOBPARP15PARP14PTGER1 | |
| SCHEMBL4638452 | 0.80 | PARP10 (0.72) | PARP10MAOBPARP15PARP14ALDH1A1 | |
| SCHEMBL27828809 | 0.80 | PARP10 (0.63) | PARP10LMNAHTTRAB9A | |
| SCHEMBL21574223 | 0.79 | L3MBTL1 (0.46) | PARP10MAOBPARP15PARP14ALDH1A1 | |
| SCHEMBL28495408 | 0.79 | NPC1 (0.53) | PARP10MAOBPARP15PARP14ALDH1A1 | |
| SCHEMBL27817675 | 0.78 | MEN1 (0.65) | PARP10MAOBPARP15PARP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |