SCHEMBL28495679

SCHEMBL28495679

CC[C@H]1CC[C@H](CCc2ccc(-c3ccc(F)c(F)c3)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.42
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
GPR84 Q9NQS5 1/20 0.40
RARB P10826 2/20 0.38
RARA P10276 1/20 0.38
RARG P13631 1/20 0.38
MAOB P27338 3/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
MAOA P21397 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
KIF11 P52732 1/20 0.35
HRH3 Q9Y5N1 1/20 0.34
GRIN2B Q13224 1/20 0.34
PGR P06401 1/20 0.33
MLNR O43193 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28505848 1.00 CYP17A1 (0.42) CYP17A1CYP11B1CYP11B2GPR84RARB
SCHEMBL28495680 1.00 CYP17A1 (0.42) CYP17A1CYP11B1CYP11B2GPR84RARB
SCHEMBL10345128 0.91 CYP17A1 (0.42) CYP17A1CYP11B1CYP11B2GPR84RARB
SCHEMBL10723905 0.90 CYP17A1 (0.41) CYP17A1CYP11B1CYP11B2GPR84RARB
SCHEMBL10723919 0.90 CYP17A1 (0.41) CYP17A1CYP11B1CYP11B2GPR84RARB
SCHEMBL3165797 0.89 HRH3 (0.44) CYP17A1CYP11B1CYP11B2GPR84SLC6A2
SCHEMBL3165806 0.89 HRH3 (0.44) CYP17A1CYP11B1CYP11B2GPR84SLC6A2
SCHEMBL9504614 0.88 GPR84 (0.40) GPR84RARBRARARARGMAOB
SCHEMBL21592063 0.88 HRH3 (0.42) CYP17A1CYP11B1CYP11B2GPR84RARB
SCHEMBL9504609 0.88 GPR84 (0.40) GPR84RARBRARARARGMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112142546-A Separation and enrichment method of trans-cyclohexyl-containing organic molecules 湖南经世新材料有限责任公司 2020-12-29 CN disclosed