Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2846406 | 0.85 | TAAR1 (0.38) | TAAR1HTR2ACHRNB2CHRNA4NISCH | |
| SCHEMBL2846427 | 0.80 | TSHR (0.32) | TAAR1TSHR | |
| SCHEMBL2856670 | 0.80 | TAAR1 (0.43) | TAAR1HTR2ACHRNB2CHRNA4NISCH | |
| SCHEMBL2854573 | 0.77 | TAAR1 (0.41) | TAAR1HTR2ACHRNB2CHRNA4NISCH | |
| SCHEMBL2852138 | 0.76 | TAAR1 (0.39) | TAAR1HTR2ACHRNB2CHRNA4NISCH | |
| SCHEMBL2850051 | 0.74 | CYP3A4 (0.42) | TAAR1HTR2ACHRNB2CHRNA4NISCH | |
| SCHEMBL2912079 | 0.73 | TP53 (0.36) | TSHR | |
| SCHEMBL30616094 | 0.73 | TP53 (0.36) | TSHR | |
| SCHEMBL27931977 | 0.69 | PNMT (0.41) | TAAR1LOXL2 | |
| SCHEMBL516440 | 0.69 | ESR1 (0.48) | TAAR1HTR2ACHRNB2CHRNA4NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | claimed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | claimed |
| US-8436111-B2 | Nickel catalyst system for the preparation of high CIS polybutadiene | BRIDGESTONE CORPORATION (JP) | 2013-05-07 | — | — | US | disclosed |
| US-20100093920-A1 | NICKEL CATALYST SYSTEM FOR THE PREPARATION OF HIGH CIS POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2010-04-15 | — | — | US | disclosed |