SCHEMBL2849617

SCHEMBL2849617

Oc1ccccc1-c1cc2cc3nc(cc4ccc(cc5nc(cc1[nH]2)C=C5)[nH]4)C=C3

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F7 P08709 1/20 0.40
▸ STAT3 P40763 1/20 0.40
▸ STAT1 P42224 1/20 0.40
▸ MGAM O43451 2/20 0.39
▸ KDM4E B2RXH2 3/20 0.38
▸ HPGD P15428 2/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ PDE5A O76074 1/20 0.38
▸ GAA P10253 2/20 0.38
▸ SI P14410 1/20 0.38
▸ MGAM2 Q2M2H8 1/20 0.38
▸ F2 P00734 1/20 0.36
▸ F10 P00742 1/20 0.36
▸ PLG P00747 1/20 0.36
▸ PLAU P00749 1/20 0.36
▸ PLAT P00750 1/20 0.36
▸ HPN P05981 1/20 0.36
▸ PRSS1 P07477 1/20 0.36
▸ PRSS2 P07478 1/20 0.36
▸ PRSS3 P35030 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28133022 1.00 F7 (0.40) F7STAT3STAT1MGAMKDM4E
SCHEMBL740996 0.91 F7 (0.35) F7STAT3STAT1MGAMKDM4E
SCHEMBL5013620 0.85 STAT3 (0.40) F7STAT3STAT1MGAMKDM4E
SCHEMBL1496170 0.84 STAT3 (0.33) STAT3STAT1
SCHEMBL5487566 0.82 NPC1 (0.42) STAT3STAT1MGAMHPGDGAA
SCHEMBL29062202 0.82 STAT3 (0.40) STAT3STAT1
SCHEMBL29489406 0.82 NPC1 (0.42) STAT3STAT1KDM4EHPGDHSD17B10
SCHEMBL5013661 0.82 STAT3 (0.40) STAT3STAT1KDM4EHPGDHSD17B10
SCHEMBL9764311 0.82 KDM4E (0.42) STAT3STAT1MGAMKDM4EHPGD
SCHEMBL5067202 0.82 NPC1 (0.42) STAT3STAT1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114497724-B Solid electrolyte and preparation method and application thereof 苏州大学张家港工业技术研究院 2023-05-23 — — CN claimed
CN-114497724-A Solid electrolyte and preparation method and application thereof 苏州大学张家港工业技术研究院 2022-05-13 — — CN claimed
CN-111261884-B Carbon material with yolk shell structure and preparation method and application thereof 中国科学院大连化学物理研究所 2021-02-12 — — CN claimed
CN-111261884-A Carbon material with yolk shell structure and preparation method and application thereof 中国科学院大连化学物理研究所 2020-06-09 — — CN claimed
CN-109381428-A Nanometer formulation for the treatment of photodynamic therapy combined immunization 复旦大学 2019-02-26 — — CN claimed
CN-103193786-A Water-soluble fullerene-tetra(p-hydroxy phenyl) porphyrin as well as preparation method and application thereof INST NUCLEAR PHYSICS & CHEMISTRY CHINA ACAD ENG PHYSICS 2013-07-10 — — CN claimed
CN-1754097-A Active oxygen species measuring device YUASA MAKOTO (JP) 2006-03-29 — — CN claimed
CN-1605026-A Electrode for active oxygen species and sensor using the electrode MAKOTO YUASA (JP) 2005-04-06 — — CN claimed
EP-0959879-B1 PHOTODYNAMIC THERAPY FOR THE TREATMENT OF OSTEOARTHRITIS GEN HOSPITAL CORP (US) 2004-05-06 — — EP claimed
CN-1090022-C Cancer treatment by photodynamic therapy, in combination with an immunoadjuvant WOUND HEALING OF OKLAHOMA (US) 2002-09-04 — — CN claimed
EP-0337601-B1 PORPHYRINS AND MEDICAMENTS FOR CANCER TREATMENT SCOTIA HOLDINGS PLC (GB) 1993-05-05 — — EP claimed
US-20250143897-A1 STENT-CONTAINING MEDICAL DEVICES AND METHODS OF USING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-05-08 — — US disclosed
CN-119552125-A Compounds and compositions for ocular treatment 艾弗德罗股份有限公司 2025-03-04 — — CN disclosed
CN-113811527-B Bis (biaziridine) derivatives as photocrosslinkers for the treatment of keratolytic disorders 艾弗德罗股份有限公司 2024-12-31 — — CN disclosed
CN-114072149-B Compounds and compositions for ocular treatment 艾弗德罗股份有限公司 2024-11-12 — — CN disclosed
US-5162519-A Porphyrins and cancer treatment EFAMOL HOLDINGS PLC (GB) 1992-11-10 — — US disclosed
US-4992257-A Dihydroporphyrins and method of treating tumors EFAMOL HOLDINGS PLC (GB) 1991-02-12 — — US disclosed
US-4957615-A POLYMER MEMBRANE WHICH CONTAINS PORPHYRIN TERUMO KABUSHIKI KAISHA (JP) 1990-09-18 — — US disclosed
US-4861454-A PORPHYRINS TERUMO KABUSHIKI KAISHA (JP) 1989-08-29 — — US disclosed
EP-0235016-A2 Oxygen sensor TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1987-09-02 — — EP disclosed
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