Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | SI | P14410 | 4/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL28139724 | 0.87 | ALDH1A1 (0.36) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28755100 | 0.85 | STAT3 (0.40) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7260895 | 0.84 | SMN1; SMN2 (0.43) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL29489406 | 0.82 | NPC1 (0.42) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL5067202 | 0.82 | NPC1 (0.42) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL5013661 | 0.82 | STAT3 (0.40) | NPC1ALDH1A1RAB9AHPGDSTAT3 | |
| SCHEMBL2849617 | 0.82 | F7 (0.40) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL29062202 | 0.82 | STAT3 (0.40) | STAT3STAT1 | |
| SCHEMBL9764311 | 0.82 | KDM4E (0.42) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL27596488 | 0.82 | STAT3 (0.40) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980004-A | Porphyrin nanovesicles with fatty acid conjugates | 大学健康网络 | 2024-05-03 | — | — | CN | claimed |
| CN-115403780-A | Photosensitizer material, preparation method and application thereof in preparation of polymer | 合肥工业大学 | 2022-11-29 | — | — | CN | claimed |
| CN-106474474-B | Photo-thermal nano particle based on peptide and photosensitizer, preparation method and application thereof | 中国科学院过程工程研究所 | 2020-02-14 | — | — | CN | claimed |
| CN-106659684-A | Peptide-containing porphyrin lipid nanovesicles | 大学健康网络 | 2017-05-10 | — | — | CN | claimed |
| CN-106474474-A | A kind of photo-thermal nanoparticle based on peptide and photosensitizer, Preparation Method And The Use | 中国科学院过程工程研究所 | 2017-03-08 | — | — | CN | claimed |
| CN-102573914-B | Porphyrin nanovesicles | 大学健康网络 | 2016-06-29 | — | — | CN | claimed |
| CN-104080929-A | Giant porphyrin-phospholipid vesicles | UNIV HEALTH NETWORK | 2014-10-01 | — | — | CN | claimed |
| CN-103930137-A | Porphyrin-phospholipid conjugate microbubbles and their use as contrast agents. | UNIV HEALTH NETWORK | 2014-07-16 | — | — | CN | claimed |
| CN-103857384-A | Method for synthesizing porphyrin-phospholipid conjugates | UNIV HEALTH NETWORK | 2014-06-11 | — | — | CN | claimed |
| CN-102573914-A | Porphyrin nanovesicles | UNIV HEALTH NETWORK | 2012-07-11 | — | — | CN | claimed |
| CN-115403780-B | Photosensitizer material, preparation method and application thereof in preparation of polymer | 合肥工业大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-117980004-A | Porphyrin nanovesicles with fatty acid conjugates | 大学健康网络 | 2024-05-03 | — | — | CN | disclosed |
| CN-116744909-A | Metal organic frameworks deliver small and biological macromolecules for cancer immunotherapy | 芝加哥大学 | 2023-09-12 | — | — | CN | disclosed |
| CN-116249525-A | Nanoparticles containing multiple cleavable prodrugs for cancer therapy | 芝加哥大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-111194232-B | Nanoscale metal-organic layer and metal-organic nanosheet | 芝加哥大学 | 2023-01-31 | — | — | CN | disclosed |
| WO-2007064841-A2 | PORPHYRINIC COMPOUNDS FOR USE IN FLOW CYTOMETRY | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-06-07 | — | — | WO | disclosed |
| EP-1763317-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | North Carolina State University (US) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006016943-A1 | SYNTHESIS OF PORPHYRINS DESIGNED FOR ATTACHMENT TO ELECTROACTIVE SURFACES VIA ONE OR MORE CARBON TETHERS | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-02-16 | — | — | WO | disclosed |
| CN-1043143-C | Beta, beta-dihydroxy meso-substituted chlorins, isobacteriochlorins, bacteriochlorins, and methods of making said compounds from beta, beta-unsubstituted tetrapyrrolic macrocycles | UNIV BRITISH COLUMBIA (CA) | 1999-04-28 | — | — | CN | disclosed |
| CN-1161697-A | Beta, beta '-dihydroxy meso-substituted chlorins, isobacteriochlorins, bacteriochlorins, and methods of making said compounds from beta, beta' -unsubstituted tetrapyrrolic macrocycles | UNIV BRITISH COLUMBIA (CA) | 1997-10-08 | — | — | CN | disclosed |