Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28487784 | 0.82 | MAPK14 (0.44) | MAPK14P2RX7HTTMEN1KMT2A | |
| SCHEMBL28500694 | 0.81 | CHRM1 (0.50) | P2RX7MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL28486486 | 0.81 | HPGD (0.53) | MAPK14P2RX7HTTMEN1KMT2A | |
| SCHEMBL28494973 | 0.75 | MAPK14 (0.45) | MAPK14P2RX7HTTMEN1KMT2A | |
| SCHEMBL19939512 | 0.73 | BRD4 (0.53) | SMN1; SMN2L3MBTL1BRD4BRD2BRD3 | |
| SCHEMBL10017252 | 0.73 | MAPK14 (0.51) | MAPK14HTTKMT2ABRD4BRD2 | |
| SCHEMBL17420665 | 0.73 | BRD4 (0.53) | MAPK14SMN1; SMN2BRD4BRD2BRD3 | |
| SCHEMBL27383587 | 0.71 | MAPK14 (0.58) | MAPK14HTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28494571 | 0.71 | BRD4 (0.45) | MAPK14P2RX7L3MBTL1BRD4BRD2 | |
| SCHEMBL5115615 | 0.69 | HPGD (0.67) | MEN1KMT2ACYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925320-A | Method for efficiently synthesizing polysubstituted 2-pyridone compound | 武汉大学 | 2020-11-13 | — | — | CN | disclosed |