Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | BRD2 | P25440 | 1/20 | 0.45 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.45 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28494973 | 0.82 | MAPK14 (0.45) | BRD4BRD2BRD3BRDTPLA2G2A | |
| SCHEMBL28486486 | 0.74 | HPGD (0.53) | BRD4BRD2BRD3BRDTP2RX7 | |
| SCHEMBL3181686 | 0.74 | BRD4 (0.56) | BRD4BRD2BRD3BRDTL3MBTL1 | |
| SCHEMBL28487784 | 0.72 | MAPK14 (0.44) | BRD4BRD2BRD3BRDTP2RX7 | |
| SCHEMBL28496256 | 0.71 | MAPK14 (0.43) | BRD4BRD2BRD3BRDTP2RX7 | |
| SCHEMBL1641959 | 0.70 | KDM4E (0.48) | BRD4BRD2BRD3BRDTTSHR | |
| SCHEMBL3623804 | 0.68 | CYP1A2 (0.54) | TSHRL3MBTL1 | |
| SCHEMBL30776972 | 0.68 | CYP1A2 (0.54) | TSHRL3MBTL1 | |
| SCHEMBL11316074 | 0.68 | BRD4 (0.70) | BRD4BRD2BRD3BRDTP2RX7 | |
| SCHEMBL21190075 | 0.68 | GAA (0.51) | TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111925320-A | Method for efficiently synthesizing polysubstituted 2-pyridone compound | 武汉大学 | 2020-11-13 | — | — | CN | disclosed |