Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | BRD3 | Q15059 | 12/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CDC42 | P60953 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | RB1 | P06400 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4194096 | 0.87 | CYP2D6 (0.58) | PRMT5CYP2D6BRD3GAACASP6 | |
| Hydrochloric Acid SCHEMBL4156764 | 0.86 | BRD3 (0.58) | PRMT5CYP2D6BRD3GAACASP6 | |
| SCHEMBL28497054 | 0.83 | GAA (0.64) | PRMT5CYP2D6BRD3GAACASP6 | |
| SCHEMBL28489487 | 0.83 | PRMT5 (0.59) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL4196072 | 0.83 | CYP2D6 (0.67) | PRMT5CYP2D6BRD3GAACASP6 | |
| SCHEMBL29896522 | 0.82 | CYP2D6 (0.60) | PRMT5CYP2D6BRD3GAACASP6 | |
| SCHEMBL20615543 | 0.82 | CYP2D6 (0.60) | PRMT5CYP2D6BRD3GAACASP6 | |
| SCHEMBL4161148 | 0.82 | CYP2D6 (0.60) | PRMT5CYP2D6BRD3GAACASP6 | |
| SCHEMBL4184731 | 0.82 | CYP2D6 (0.63) | PRMT5CYP2D6BRD3GAACASP6 | |
| Hydrochloric Acid SCHEMBL4157190 | 0.82 | CYP2D6 (0.66) | PRMT5CYP2D6BRD3GAACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739371-B | Tetrahydrocarbazole micromolecule organic compound, application thereof in preparing antibacterial drugs and preparation method thereof | 华东师范大学 | 2020-08-25 | — | — | CN | disclosed |