Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.59 |
| ▸ | BRD3 | Q15059 | 14/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CDC42 | P60953 | 1/20 | 0.47 |
| ▸ | RB1 | P06400 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28497875 | 0.83 | GAA (0.69) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL28496378 | 0.83 | PRMT5 (0.58) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL28487334 | 0.81 | PRMT5 (0.62) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL31497455 | 0.80 | RB1 (0.52) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL5455548 | 0.79 | PRMT5 (0.72) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL5447038 | 0.77 | BRD3 (0.63) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL5468025 | 0.76 | BRD3 (0.67) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL22118719 | 0.75 | CYP2D6 (0.55) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL28731952 | 0.75 | CYP2D6 (0.55) | PRMT5BRD3GAACASP6CDC42 | |
| SCHEMBL13702966 | 0.74 | PRMT5 (1.00) | PRMT5BRD3GAACASP6CDC42 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739371-B | Tetrahydrocarbazole micromolecule organic compound, application thereof in preparing antibacterial drugs and preparation method thereof | 华东师范大学 | 2020-08-25 | — | — | CN | disclosed |