Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK1D | Q8IU85 | 14/20 | 0.65 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.48 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.41 |
| ▸ | CAMK1 | Q14012 | 1/20 | 0.41 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.41 |
| ▸ | PNCK | Q6P2M8 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28496449 | 1.00 | CAMK1D (0.65) | CAMK1DROCK2PIP5K1CCYP2C9CYP2C19 | |
| SCHEMBL28490794 | 0.97 | CAMK1D (0.64) | CAMK1DROCK2PIP5K1CCYP2C9CYP2C19 | |
| SCHEMBL28490797 | 0.97 | CAMK1D (0.64) | CAMK1DROCK2PIP5K1CCYP2C9CYP2C19 | |
| SCHEMBL23113451 | 0.79 | CAMK1D (1.00) | CAMK1DPIP5K1CCYP2C9CYP2C19KCNH2 | |
| SCHEMBL23113449 | 0.79 | CAMK1D (1.00) | CAMK1DPIP5K1CCYP2C9CYP2C19KCNH2 | |
| SCHEMBL28499389 | 0.77 | CAMK1D (0.65) | CAMK1DROCK2PIP5K1CCYP2C9CYP2C19 | |
| SCHEMBL28499387 | 0.77 | CAMK1D (0.65) | CAMK1DROCK2PIP5K1CCYP2C9CYP2C19 | |
| SCHEMBL23113323 | 0.76 | CAMK1D (1.00) | CAMK1DPIP5K1CCYP2C9CYP2C19KCNH2 | |
| SCHEMBL23113321 | 0.76 | CAMK1D (1.00) | CAMK1DPIP5K1CCYP2C9CYP2C19KCNH2 | |
| SCHEMBL28488317 | 0.74 | CAMK1D (0.67) | CAMK1DROCK2PIP5K1CCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112119077-A | Kinase inhibitors | 曼彻斯特大学 | 2020-12-22 | — | — | CN | disclosed |