Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3481615 | 0.77 | ESR1 (0.34) | TP53KDM4EALDH1A1GAAHPGD | |
| SCHEMBL28218923 | 0.75 | TP53 (0.38) | TP53KDM4EALDH1A1GAAHPGD | |
| SCHEMBL3889886 | 0.75 | NR1H2 (0.50) | TP53KDM4EALDH1A1GAAHPGD | |
| SCHEMBL10730048 | 0.75 | ESR1 (0.45) | TP53KDM4EALDH1A1GAAHPGD | |
| SCHEMBL20637319 | 0.73 | ESR1 (0.38) | TP53KDM4EALDH1A1GAAHPGD | |
| SCHEMBL12879487 | 0.73 | MAPT (0.42) | TP53KDM4EALDH1A1GAAHPGD | |
| SCHEMBL13089067 | 0.73 | ESR1 (0.38) | TP53KDM4EALDH1A1GAAHPGD | |
| SCHEMBL21383132 | 0.71 | TP53 (0.35) | TP53KDM4EALDH1A1GAAHPGD | |
| SCHEMBL21383286 | 0.71 | TP53 (0.35) | TP53KDM4EALDH1A1GAAHPGD | |
| SCHEMBL20637391 | 0.71 | NR1H2 (0.42) | TP53KDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110950-B | Preparation method of disilane | 杭州师范大学 | 2023-02-14 | — | — | CN | disclosed |
| CN-112110950-A | Preparation method of disilane | 杭州师范大学 | 2020-12-22 | — | — | CN | disclosed |