SCHEMBL28496809

SCHEMBL28496809

O=C(c1ccccc1)c1ccc(O)c(Oc2ccccc2)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.50
KDM4E B2RXH2 4/20 0.50
HSD17B10 Q99714 4/20 0.50
ALOX15 P16050 3/20 0.50
MAPK1 P28482 2/20 0.50
HPGD P15428 4/20 0.49
ALDH1A1 P00352 3/20 0.49
LMNA P02545 3/20 0.49
HTT P42858 2/20 0.49
CYP1A2 P05177 1/20 0.49
PGR P06401 1/20 0.49
CYP2D6 P10635 1/20 0.49
SLC6A2 P23975 1/20 0.49
PDE4A P27815 1/20 0.49
CYP2C19 P33261 1/20 0.49
HRH1 P35367 1/20 0.49
SLC6A3 Q01959 1/20 0.49
PDE4D Q08499 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2879413 0.90 HPGD (0.50) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL21275711 0.89 HPGD (0.52) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL5844713 0.87 POLB (0.53) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL2872542 0.86 HPGD (0.48) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL2877480 0.84 MAPT (0.46) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL27677099 0.82 STAT3 (0.45) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL23422729 0.82 MAPT (0.51) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL25381912 0.82 MAPT (0.64) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL15313718 0.81 KDM4E (0.61) MAPTKDM4EHSD17B10ALOX15MAPK1
SCHEMBL2879025 0.77 BCL2 (0.59) MAPTKDM4EHSD17B10ALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851912-B A3+ B2 type hyperbranched epoxy resin precursor, modified composition, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-04-07 CN disclosed
CN-112851912-A A3+ B2 type hyperbranched epoxy resin precursor, modified composition, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2021-05-28 CN disclosed
CN-111777642-B Halogen-free flame-retardant unsaturated polyester composition, polyester product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2020-12-11 CN disclosed
CN-111808233-B Halogen-free flame-retardant acrylic resin composition, molding compound product, preparation method and application 中国科学院宁波材料技术与工程研究所 2020-12-11 CN disclosed
CN-111808233-A Halogen-free flame-retardant acrylic resin composition, molding compound product, preparation method and application 中国科学院宁波材料技术与工程研究所 2020-10-23 CN disclosed
CN-111777642-A Halogen-free flame-retardant unsaturated polyester composition, polyester product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2020-10-16 CN disclosed