SCHEMBL5844713

SCHEMBL5844713

O=C(c1ccccc1)c1ccc(C(=O)O)c(Oc2ccccc2)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
KDM4E B2RXH2 2/20 0.50
MAPK1 P28482 2/20 0.50
AKR1C3 P42330 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
SRD5A2 P31213 3/20 0.49
CCNE2 O96020 1/20 0.46
CCNE1 P24864 1/20 0.46
CDK2 P24941 1/20 0.46
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
PGR P06401 1/20 0.45
CYP2D6 P10635 1/20 0.45
HPGD P15428 1/20 0.45
SLC6A2 P23975 1/20 0.45
PDE4A P27815 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28496809 0.87 MAPT (0.50) POLBKDM4EMAPK1AKR1C3HSD17B10
SCHEMBL2879413 0.78 HPGD (0.50) POLBKDM4EMAPK1AKR1C3HSD17B10
SCHEMBL21275711 0.77 HPGD (0.52) POLBKDM4EMAPK1HSD17B10MAPT
SCHEMBL5069965 0.76 MAPT (0.69) KDM4EMAPK1AKR1C3HSD17B10MAPT
SCHEMBL8031428 0.75 ALDH1A1 (0.54) KDM4EMAPK1AKR1C3HSD17B10MAPT
SCHEMBL2872542 0.75 HPGD (0.48) POLBKDM4EMAPK1HSD17B10MAPT
SCHEMBL21808151 0.74 MAPT (0.51) POLBMAPK1AKR1C3HSD17B10MAPT
SCHEMBL15313718 0.74 KDM4E (0.61) POLBKDM4EMAPK1HSD17B10MAPT
SCHEMBL2879025 0.74 BCL2 (0.59) POLBKDM4EMAPK1HSD17B10MAPT
SCHEMBL1801912 0.74 AKR1C3 (0.64) POLBKDM4EMAPK1AKR1C3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7125442-B2 Lightfast additive having UV-absorbing moiety and ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2006-10-24 US disclosed
US-20040237837-A1 Lightfast additive having UV-absorbing moiety and ink composition including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2004-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040237837-A1 Lightfast additive having UV-absorbing moiety and ink composition including the same CDK4, CDKL4, UGT1A4 POLB 1945/4885KDM4E 276/4885MAPK1 4233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.