Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 2/20 | 0.53 |
| ▸ | PYGM | P11217 | 2/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28376945 | 0.84 | SMN1; SMN2 (0.74) | SMN1; SMN2LMNARAB9ANPC1CYP2C9 | |
| SCHEMBL5448094 | 0.82 | MEN1 (0.72) | SMN1; SMN2RAB9ANPC1KMT2AKDM4E | |
| SCHEMBL31565200 | 0.82 | MEN1 (0.72) | SMN1; SMN2RAB9ANPC1KMT2AKDM4E | |
| SCHEMBL31565224 | 0.81 | MEN1 (0.50) | SMN1; SMN2RAB9ANPC1PYGLPYGM | |
| SCHEMBL28499435 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNARAB9ANPC1CYP2C9 | |
| SCHEMBL27388520 | 0.78 | NPC1 (0.71) | LMNARAB9ANPC1CYP2C9CYP1A2 | |
| SCHEMBL28426782 | 0.77 | GRIK1 (0.55) | SMN1; SMN2RAB9ANPC1CYP2C9CYP1A2 | |
| SCHEMBL31565248 | 0.77 | MEN1 (0.51) | LMNARAB9ANPC1PYGLPYGM | |
| SCHEMBL4783304 | 0.76 | NPC1 (0.63) | SMN1; SMN2LMNARAB9ANPC1CYP2C9 | |
| SCHEMBL6072225 | 0.76 | GRM4 (0.65) | RAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112047879-B | Method for selectively synthesizing halogenated arylamine by copper catalysis | 浙江工业大学 | 2022-01-14 | — | — | CN | disclosed |
| CN-112047879-A | Method for selectively synthesizing halogenated arylamine by copper catalysis | 浙江工业大学 | 2020-12-08 | — | — | CN | disclosed |