Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pidolic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pidolic Acid SCHEMBL28497194 | 1.00 | CNR1 (0.40) | CNR1DAGLAALDH1A1S1PR3DNM1 | |
| Pidolic Acid SCHEMBL27784562 | 0.91 | CNR1 (0.46) | CNR1DAGLAALDH1A1S1PR3LMNA | |
| Pidolic Acid SCHEMBL27784564 | 0.91 | CNR1 (0.46) | CNR1DAGLAALDH1A1S1PR3LMNA | |
| Pidolic Acid SCHEMBL27845670 | 0.85 | CNR1 (0.40) | CNR1DAGLAALDH1A1S1PR3KMT2A | |
| Pidolic Acid SCHEMBL27845669 | 0.85 | CNR1 (0.40) | CNR1DAGLAALDH1A1S1PR3KMT2A | |
| Cetyl Alcohol SCHEMBL28362301 | 0.85 | CNR1 (0.42) | CNR1DAGLAALDH1A1S1PR3MEN1 | |
| Cetyl Alcohol SCHEMBL28527381 | 0.85 | CNR1 (0.42) | CNR1DAGLAALDH1A1S1PR3MEN1 | |
| Palmitic Acid SCHEMBL10937075 | 0.84 | GPR84 (0.50) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| Dodecanoate SCHEMBL6028403 | 0.84 | GPR84 (0.50) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| Pidolic Acid SCHEMBL27800447 | 0.83 | CNR1 (0.38) | CNR1DAGLAALDH1A1S1PR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112004543-A | Compositions comprising bacterial strains | 4D制药研究有限公司 | 2020-11-27 | — | — | CN | disclosed |