Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.49 |
| ▸ | MTOR | P42345 | 15/20 | 0.49 |
| ▸ | RPTOR | Q8N122 | 7/20 | 0.49 |
| ▸ | MLST8 | Q9BVC4 | 7/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.49 |
| ▸ | RICTOR | Q6R327 | 5/20 | 0.49 |
| ▸ | MAPKAP1 | Q9BPZ7 | 5/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21658972 | 0.74 | MAP3K12 (0.48) | PIK3CAMTOR | |
| SCHEMBL29947221 | 0.72 | PIK3CA (0.50) | PIK3CAMTORPIK3CDPIK3C3CHEK1 | |
| SCHEMBL28958536 | 0.72 | PIK3CA (0.50) | PIK3CAMTORPIK3CDPIK3C3CHEK1 | |
| SCHEMBL30745619 | 0.71 | PIK3CA (0.49) | PIK3CAMTORPIK3CDPIK3C3CHEK1 | |
| SCHEMBL695787 | 0.69 | GSK3B (0.70) | — | |
| SCHEMBL9943990 | 0.69 | GSK3B (0.70) | — | |
| SCHEMBL8232098 | 0.69 | GSK3B (0.70) | — | |
| SCHEMBL24398697 | 0.68 | MTOR (0.92) | PIK3CAMTORRPTORMLST8PIK3R1 | |
| SCHEMBL19616562 | 0.68 | MTOR (0.90) | PIK3CAMTORRPTORMLST8PIK3R1 | |
| SCHEMBL17748652 | 0.68 | MTOR (0.92) | PIK3CAMTORRPTORMLST8PIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109414415-B | Treatment of skin lesions | 拓客股份有限公司 | 2023-05-02 | — | — | CN | claimed |
| CN-107108644-B | Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines | 皮奎尔治疗公司 | 2021-01-05 | — | — | CN | claimed |
| CN-109414415-B | Treatment of skin lesions | 拓客股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-109475560-B | Treatment of neurological disorders | 巴塞尔大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-107108644-B | Difluoromethyl-aminopyridines and difluoromethyl-aminopyrimidines | 皮奎尔治疗公司 | 2021-01-05 | — | — | CN | disclosed |