Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.49 |
| ▸ | ATR | Q13535 | 11/20 | 0.47 |
| ▸ | ATRIP | Q8WXE1 | 8/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 5/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28958536 | 0.98 | PIK3CA (0.50) | PIK3CAPIK3CDATRATRIPCHEK1 | |
| SCHEMBL29947221 | 0.98 | PIK3CA (0.50) | PIK3CAPIK3CDATRATRIPCHEK1 | |
| SCHEMBL29525850 | 0.80 | AURKA (0.42) | PIK3CAPIK3CDATRATRIPCHEK1 | |
| SCHEMBL28539901 | 0.79 | ATR (0.55) | PIK3CAPIK3CDATRATRIPCHEK1 | |
| SCHEMBL28539899 | 0.79 | ATR (0.55) | PIK3CAPIK3CDATRATRIPCHEK1 | |
| SCHEMBL2127456 | 0.79 | ATR (0.55) | PIK3CAPIK3CDATRATRIPCHEK1 | |
| SCHEMBL29442179 | 0.79 | ATR (0.55) | PIK3CAPIK3CDATRATRIPCHEK1 | |
| SCHEMBL26972646 | 0.78 | GRM1 (0.40) | — | |
| SCHEMBL30629341 | 0.77 | PIK3CD (0.58) | PIK3CAPIK3CDATRATRIPCHEK1 | |
| SCHEMBL30288871 | 0.76 | PIK3C3 (0.52) | PIK3CAATRATRIPCHEK1PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135659-B | Morpholine derivative, and preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2024-03-12 | — | — | CN | disclosed |