Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | BCHE | P06276 | 12/20 | 0.56 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963493 | 1.00 | MAPK1 (0.65) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL22778911 | 0.93 | MAPK1 (0.65) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL1926806 | 0.87 | NOX1 (0.69) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL396464 | 0.84 | BCHE (0.71) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL522271 | 0.82 | BCHE (0.70) | BCHENOX1ACHE | |
| SCHEMBL30882096 | 0.82 | BCHE (0.70) | BCHENOX1ACHE | |
| SCHEMBL30743852 | 0.82 | BCHE (0.70) | BCHENOX1ACHE | |
| Hydrochloric Acid SCHEMBL27211953 | 0.80 | BCHE (0.68) | MAPK1BCHENOX1ACHE | |
| SCHEMBL9560319 | 0.79 | SNCA (0.66) | MAPK1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL29557693 | 0.79 | MAPK1 (0.67) | MAPK1MEN1KMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112225731-B | FAP alpha specific recognition methylene blue derivative with tumor diagnosis and treatment functions and preparation method and application thereof | 中山大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-112225731-A | FAP alpha specific recognition methylene blue derivative with tumor diagnosis and treatment functions and preparation method and application thereof | 中山大学 | 2021-01-15 | — | — | CN | disclosed |