SCHEMBL396464

SCHEMBL396464

CNC(=O)N1c2ccccc2Sc2cc(N(C)C)ccc21

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
BCHE P06276 15/20 0.71
ACHE P22303 1/20 0.71
MAPK1 P28482 2/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
MAPT P10636 2/20 0.51
GAA P10253 1/20 0.51
LMNA P02545 1/20 0.51
NPSR1 Q6W5P4 1/20 0.49
NOX1 Q9Y5S8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL244827 0.93 MAPK1 (0.62) BCHEACHEMAPK1MEN1KMT2A
SCHEMBL29384821 0.93 MAPK1 (0.62) BCHEACHEMAPK1MEN1KMT2A
SCHEMBL1926806 0.85 NOX1 (0.69) BCHEACHEMAPK1MEN1KMT2A
SCHEMBL1828806 0.84 KMT2A (0.59) BCHEACHEMAPK1MEN1KMT2A
SCHEMBL28497697 0.84 MAPK1 (0.65) BCHEACHEMAPK1MEN1KMT2A
SCHEMBL30963493 0.84 MAPK1 (0.65) BCHEACHEMAPK1MEN1KMT2A
SCHEMBL22726424 0.81 MAPK1 (0.60) BCHEACHEMAPK1MEN1KMT2A
SCHEMBL3312945 0.80 MAPK1 (0.59) BCHEACHEMAPK1MEN1KMT2A
SCHEMBL23393557 0.78 BCHE (0.61) BCHEACHEMAPK1MEN1KMT2A
SCHEMBL29849039 0.78 BCHE (0.61) BCHEACHEMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5223404-A Chromogen, oxidase, compound which releases rate enhancer in presence of peptidase SUNSTAR KABUSHIKI KAISHA (JP) 1993-06-29 US claimed
US-12264356-B2 Method for determining sensitivity to SGLT2 inhibitor and sensitivity marker for SGLT2 inhibitor NIHON UNIVERSITY (JP) 2025-04-01 US disclosed
EP-3461907-B1 MEASUREMENT OF GLYCOPROTEIN ARKRAY INC (JP) 2023-06-14 EP disclosed
US-10989714-B2 Measurement of glycoprotein ARKRAY, INC. (JP) 2021-04-27 US disclosed
US-20200347458-A1 METHOD FOR DETERMINING SENSITIVITY TO SGLT2 INHIBITOR AND SENSITIVITY MARKER FOR SGLT2 INHIBITOR NIHON UNIVERSITY (JP) 2020-11-05 US disclosed
US-20190137502-A1 Measurement of Glycoprotein ARKRAY, INC. (JP) 2019-05-09 US disclosed
EP-3461907-A1 MEASUREMENT OF GLYCOPROTEIN ARKRAY, Inc. (JP) 2019-04-03 EP disclosed
EP-2319937-B1 BLOOD COMPONENT MEASUREMENT METHOD UTILIZING HEMOLYZED WHOLE BLOOD, AND KIT FOR THE METHOD NIPPON KAYAKU KK (JP) 2016-01-27 EP disclosed
US-8883439-B2 Blood component measurement method utilizing hemolyzed whole blood, and kit for the method NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-11-11 US disclosed
US-8753832-B2 Method of assaying 1,5 anhydroglucitol by using whole blood and measurement kit NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-06-17 US disclosed
EP-0533183-B1 Composition for the measurement of potassium ion concentration TOYO BOSEKI (JP) 1997-12-29 EP disclosed
US-5426033-A Accurate quantitative analysis KYOWA MEDEX CO., LTD. (JP) 1995-06-20 US disclosed
EP-0608795-A1 Method for enzymatic determination of substrate after enzymatically removing galactose Kyowa Medex Co. Ltd. (JP) 1994-08-03 EP disclosed
US-5334507-A Pyruvate kinase, glycerol kinase, glycerol-3-phosphate oxidase, peroxidase, reduced chromogen, adenosine diphosphate, phosphoenolpyruvic acid TOYO BOSEKI KABUSHIKI KAISHA (JP) 1994-08-02 US disclosed
EP-0533183-A2 Composition for the measurement of potassium ion concentration TOYO BOSEKI KABUSHIKI KAISHA Trading under the name of Toyobo Co., Ltd. (JP) 1993-03-24 EP disclosed
EP-0174371-B1 TRIPHENYLMETHANE DERIVATIVES AND METHOD FOR DETERMINING OXIDATIVE SUBSTANCES USING THEM AS COLOR-FORMING COMPONENT WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1990-09-19 EP disclosed
US-4778753-A IN PRESCENCE OF URICASE, METAL CHELATE AND ANIONIC SURFACTANT; WITHOUT COLORING INTERFERENCE WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 1988-10-18 US disclosed
US-4673635-A Triphenyl methane derivatives and method of quantitatively measuring an oxidative substance WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 1987-06-16 US disclosed
US-4613465-A HYDROGEN PEROXIDE, BODY FLUIDS, ENZYMES WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 1986-09-23 US disclosed
EP-0174371-A1 TRIPHENYLMETHANE DERIVATIVES AND METHOD FOR DETERMINING OXIDATIVE SUBSTANCES USING THEM AS COLOR-FORMING COMPONENT WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1986-03-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10989714-B2 Measurement of glycoprotein ENGASE, UGGT1, ST6GAL1 BCHE 703/4885ACHE 1316/4885MAPK1 4555/4885
US-20190137502-A1 Measurement of Glycoprotein ENGASE, UGGT1, ST6GAL1 BCHE 703/4885ACHE 1316/4885MAPK1 4555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.