Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPS1 | P31327 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16150924 | 0.86 | RXFP1 (0.44) | CPS1MAPTRXFP1FASNHTT | |
| SCHEMBL17389928 | 0.85 | FASN (0.49) | CPS1MAPTRXFP1FASNHTT | |
| SCHEMBL16149873 | 0.81 | RXFP1 (0.40) | CPS1MAPTRXFP1FASNHTT | |
| SCHEMBL22926299 | 0.79 | MAPT (0.41) | CPS1MAPTRXFP1FASNHTT | |
| Hydrochloric Acid SCHEMBL17389942 | 0.79 | RXFP1 (0.43) | CPS1MAPTRXFP1 | |
| SCHEMBL16150156 | 0.78 | MAPT (0.36) | CPS1MAPTRXFP1FASNHTT | |
| SCHEMBL23641648 | 0.76 | RXFP1 (0.45) | MAPTRXFP1FASNTP53CA1 | |
| SCHEMBL17404611 | 0.74 | FASN (0.49) | MAPTRXFP1FASNHTTTSHR | |
| SCHEMBL16150679 | 0.72 | FASN (0.64) | MAPTRXFP1FASNHTTKDM4E | |
| SCHEMBL16151197 | 0.68 | MAPT (0.49) | MAPTRXFP1FASNHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521369-A | Compounds and compositions for inhibition of FASN | 福马治疗股份有限公司 | 2021-03-19 | — | — | CN | disclosed |
| CN-105492008-B | Compounds and compositions for inhibition of FASN | 福马治疗股份有限公司 | 2020-11-27 | — | — | CN | disclosed |