Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3441777 | 0.81 | MAOA (0.61) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL1539929 | 0.79 | MAOA (0.64) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL3614466 | 0.79 | MAOA (0.59) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL24688181 | 0.79 | MAOA (0.64) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL3614462 | 0.79 | MAOA (0.59) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL7529147 | 0.78 | MAOA (0.68) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL14223690 | 0.76 | MAOA (0.60) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL26648419 | 0.76 | MAOA (0.60) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL26648827 | 0.76 | MAOA (0.71) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| Dimethylamine SCHEMBL553293 | 0.75 | MAOA (0.58) | MAOAMAOBALDH1A1MAPK1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105360-B | BCL-2 protein degrading agent for cancer treatment | 生物风险投资有限责任公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-112105360-A | BCL-2 protein degrading agents for cancer treatment | 生物风险投资有限责任公司 | 2020-12-18 | — | — | CN | disclosed |