SCHEMBL28498446

SCHEMBL28498446

O=CNC1CCCC(C(=O)O)C1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 4/20 0.58
ADH1A P07327 4/20 0.58
ADH1C P00326 3/20 0.58
ADH7 P40394 2/20 0.58
ADH4 P08319 1/20 0.50
BTK Q06187 1/20 0.47
EPHX2 P34913 1/20 0.45
TSHR P16473 2/20 0.42
ANPEP P15144 1/20 0.37
ACE P12821 1/20 0.36
SLC6A1 P30531 2/20 0.35
LMNA P02545 2/20 0.35
SLC6A11 P48066 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC6A13 Q9NSD5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18534809 0.82 ADH1B (0.56) ADH1BADH1AADH1CADH7ADH4
SCHEMBL28262435 0.79 ADH1B (0.52) ADH1BADH1AADH1CADH7ADH4
SCHEMBL9977768 0.79 BTK (0.54) ADH1BADH1AADH1CADH7BTK
SCHEMBL23716723 0.79 BTK (0.54) ADH1BADH1AADH1CADH7BTK
SCHEMBL805181 0.79 BTK (0.54) ADH1BADH1AADH1CADH7BTK
SCHEMBL8863326 0.77 ADH1B (0.64) ADH1BADH1AADH1CADH7ADH4
SCHEMBL10437988 0.77 ADH1B (0.64) ADH1BADH1AADH1CADH7ADH4
SCHEMBL20678788 0.75 ADH1B (0.62) ADH1BADH1AADH1CADH7ADH4
SCHEMBL4924938 0.75 ADH1B (0.62) ADH1BADH1AADH1CADH7ADH4
SCHEMBL13457725 0.75 ADH1B (0.62) ADH1BADH1AADH1CADH7ADH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111886217-A Process for producing cyclohexanedicarboxylic acids, dicyanocyclohexanes, and bis (aminomethyl) cyclohexanes 三菱瓦斯化学株式会社 2020-11-03 CN disclosed