SCHEMBL28498657

SCHEMBL28498657

CCc1nccnc1C(C)=NNC(N)=S.[Cu]

nearest known ligand 0.51

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
METTL3 Q86U44 2/20 0.43
ATM Q13315 1/20 0.43
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28454239 0.98 METTL3 (0.44) METTL3ATMHTT
SCHEMBL28457486 0.97 METTL3 (0.43) METTL3ATMHTT
SCHEMBL9876312 0.79 MAPK1 (0.36) HTT
SCHEMBL9876314 0.79 MAPK1 (0.36) HTT
SCHEMBL9876553 0.74
SCHEMBL4380049 0.72 ATM (0.51) METTL3ATM
SCHEMBL2493220 0.69 NCOA3 (0.54) METTL3ATM
SCHEMBL28199380 0.69 ATM (0.48) METTL3ATM
SCHEMBL3461163 0.68 TSHR (0.38)
SCHEMBL31008793 0.68 TSHR (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108912149-B Copper compound with 2-acetyl-3-ethylpyrazine thiosemicarbazone as ligand and synthetic method and application thereof 广西师范大学 2020-12-22 CN disclosed