Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK1D | Q8IU85 | 8/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 9/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.42 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | BLK | P51451 | 1/20 | 0.40 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.40 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23113161 | 0.79 | CAMK1D (1.00) | CAMK1DMAP3K7CSF1RPIM1MAPK3 | |
| SCHEMBL23113160 | 0.79 | CAMK1D (1.00) | CAMK1DMAP3K7CSF1RPIM1MAPK3 | |
| SCHEMBL28509419 | 0.73 | CAMK1D (0.70) | CAMK1DROCK2MAP3K7CSF1RPIM1 | |
| SCHEMBL28903869 | 0.73 | CAMK1D (0.64) | CAMK1DROCK2RIPK4KCNH2MAP2K5 | |
| SCHEMBL28903873 | 0.73 | CAMK1D (0.64) | CAMK1DROCK2RIPK4KCNH2MAP2K5 | |
| SCHEMBL30738704 | 0.73 | ROCK2 (0.50) | CAMK1DROCK2ROCK1PAK4PAK1 | |
| SCHEMBL28496392 | 0.72 | CAMK1D (0.67) | CAMK1DROCK2ROCK1IDH2MAP3K7 | |
| SCHEMBL28490797 | 0.71 | CAMK1D (0.64) | CAMK1DROCK2ROCK1PAK4PAK1 | |
| SCHEMBL28490794 | 0.71 | CAMK1D (0.64) | CAMK1DROCK2ROCK1PAK4PAK1 | |
| SCHEMBL28493012 | 0.71 | CAMK1D (0.70) | CAMK1DROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112119077-A | Kinase inhibitors | 曼彻斯特大学 | 2020-12-22 | — | — | CN | disclosed |